Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
GENCONCOR-1 study is translational research aimed to investigate the concordance of the molecular genetic profile of the primary tumor and brain metastases (BM) of colorectal cancer (CRC). The study was conducted by post hoc analysis of pairs of samples of histological material with determination of the mutational status of genes KRAS, NRAS, BRAF, HER2 and MSI.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Men and women over 18 years of age.
• Histologically confirmed cancer of the colon or rectum.
• Histologically confirmed metastatic lesion of the brain.
• Neurosurgical resection for brain metastases of colorectal cancer.
• Presence of paired tumor samples (both primary tumor and intracranial material).
Locations
Other Locations
Russian Federation
Blokhin's Russian Cancer Research Center
RECRUITING
Moscow
Contact Information
Primary
David Halafyan, MD
daveupnow@gmail.com
+7(930)928-00-72
Time Frame
Start Date: 2024-04-01
Estimated Completion Date: 2027-09
Participants
Target number of participants: 30
Related Therapeutic Areas
Sponsors
Leads: Blokhin's Russian Cancer Research Center